Search results for " processo"

SPECTR

2018

Modern high throughput sequencing platforms can produce large amounts of short read DNA data at low cost. Error correction is an important but time-consuming initial step when processing this data in order to improve the quality of downstream analyses. In this paper, we present a Scalable Parallel Error CorrecToR designed to improve the throughput of DNA error correction for Illumina reads on various parallel platforms. Our design is based on a k-spectrum approach where a Bloom filter is frequently probed as a key operation and is optimized towards AVX-512-based multi-core CPUs, Xeon Phi many-cores (both KNC and KNL), and heterogeneous compute clusters. A number of architecture-specific opt…

2016

The growth of next-generation sequencing (NGS) datasets poses a challenge to the alignment of reads to reference genomes in terms of alignment quality and execution speed. Some available aligners have been shown to obtain high quality mappings at the expense of long execution times. Finding fast yet accurate software solutions is of high importance to research, since availability and size of NGS datasets continue to increase. In this work we present an efficient parallelization approach for NGS short-read alignment on multi-core clusters. Our approach takes advantage of a distributed shared memory programming model based on the new UPC++ language. Experimental results using the CUSHAW3 alig…

Parallel and Space-Efficient Construction of Burrows-Wheeler Transform and Suffix Array for Big Genome Data

2016

Next-generation sequencing technologies have led to the sequencing of more and more genomes, propelling related research into the era of big data. In this paper, we present ParaBWT, a parallelized Burrows-Wheeler transform (BWT) and suffix array construction algorithm for big genome data. In ParaBWT, we have investigated a progressive construction approach to constructing the BWT of single genome sequences in linear space complexity, but with a small constant factor. This approach has been further parallelized using multi-threading based on a master-slave coprocessing model. After gaining the BWT, the suffix array is constructed in a memory-efficient manner. The performance of ParaBWT has b…

mD3DOCKxb: An Ultra-Scalable CPU-MIC Coordinated Virtual Screening Framework

2017

Molecular docking is an important method in computational drug discovery. In large-scale virtual screening, millions of small drug-like molecules (chemical compounds) are compared against a designated target protein (receptor). Depending on the utilized docking algorithm for screening, this can take several weeks on conventional HPC systems. However, for certain applications including large-scale screening tasks for newly emerging infectious diseases such high runtimes can be highly prohibitive. In this paper, we investigate how the massively parallel neo-heterogeneous architecture of Tianhe-2 Supercomputer consisting of thousands of nodes comprising CPUs and MIC coprocessors that can effic…

Extending PluTo for Multiple Devices by Integrating OpenACC

2018

For many years now, processor vendors increased the performance of their devices by adding more cores and wider vectorization units to their CPUs instead of scaling up the processors' clock frequency. Moreover, GPUs became popular for solving problems with even more parallel compute power. To exploit the full potential of modern compute devices, specific codes are necessary which are often coded in a hardware-specific manner. Usually, the codes for CPUs are not usable for GPUs and vice versa. The programming API OpenACC tries to close this gap by enabling one code-base to be suitable and optimized for many devices. Nevertheless, OpenACC is rarely used by `standard programmers' and while dif…

BREVI OSSERVAZIONI SULL’ONERE DI SPECIFICA CONTESTAZIONE E IL DIVIETO DI NOVA IN APPELLO NEL RITO DEL LAVORO: LA CORRELAZIONE TRA ONERE DI CONTESTAZI…

2015

Oggetto dell'indagine è la non contestazione nel processo del lavoro e nel processo in generale, nell'ambito delle possibili difese della parte. La sentenza della Suprema Corte 28 febbraio 2014, n. 4854, che si colloca nel solco di un diffuso orientamento giurisprudenziale in materia di c.d. rito del lavoro, offre lo spunto per una riflessione di ordine generale sui limiti della specifica contestazione e delle conseguenze della sua omissione, nel generale sistema di preclusioni del processo civile. Essa offre, inoltre, l’occasione per una ricollocazione in chiave sistematica della non contestazione nell’ambito delle c.d. eccezioni, e nella sistematica del diritto processuale.

Livländische Process-Ordnung

1701

Enfocament de resiliència comunitària per afrontar contextos d'exclusió social

2016

espanolLa pobreza y la marginacion han evolucionado a lo largo del tiempo, presentandose hoy en Europa, como un fenomeno complejo, multidimensional y dinamico, que engloba no solamente carencias economicas, sino dificultades para la insercion laboral, la participacion social y ciudadana, el uso de los recursos institucionales y el acceso a bienes basicos como la educacion, la vivienda, la salud o la cultura. La inclusion social, por su parte y para la Union Europea, se define como «un proceso que garantiza que las personas amenazadas de pobreza y exclusion social, pueden acceder a los recursos necesarios para participar, plenamente, en la vida economica, social y cultural, y que gozan de un…

Introduzione ai modelli di ADR, profili storico-comparatistici

2011

brevi cenni sul movimento ADR negli Stati uniti d'America dagli anni 50 ad oggi

L'abuso del processo: una ricerca comparatistica

2014

Abuse of process, and related expressions, such as abuse of procedural rights, have in relatively recent times become part of the legal language of continental countries, such as Italy. But, since the introduction of the use of the concept, it has increasingly been an object and aim of several doctrinal contributions, which are here scrutinized. The essay concentrates upon the evolution of legal proceedings amounting to abuse of process, according to the definition which bases itself on the unfair and inadequate use of the process for purposes profoundly differing from those typical of the individual right to the access of justice. Initially, it was the state, when prosecuting a defendant f…